Actively Recruiting

Age: 18Years +
All Genders
Healthy Volunteers
NCT06154694

Glenohumeral Joint Contract Patterns in Osteoarthritic Glenoids

Led by Universitaire Ziekenhuizen KU Leuven · Updated on 2026-04-02

156

Participants Needed

1

Research Sites

1495 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Shoulder osteoarthritis (OA) is a frequent problem in our aging population and is believed to occur in up to 20% of the population. Different types of glenoid morphology are associated with shoulder OA, depending on the amount and localization of the glenoid erosion as well as the amount and direction of Humeral Head Migration. Total shoulder arthroplasty (TSA) has been shown to relieve the pain and improve joint function of patients with OA. However, several complications such as component loosening and polyethylene damage has been reported and it has been revealed that 7.3% of glenoids may show signs of asymptomatic radiographic loosening annually after primary anatomic TSA. The mechanism of such fixation failure is still unclear. The main goal of this study is evaluating in-vivo glenohumeral contact patterns in patients with osteoarthritic glenoids before and after TSA, to unravel the high rate of glenoid component loosening.

CONDITIONS

Official Title

Glenohumeral Joint Contract Patterns in Osteoarthritic Glenoids

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with glenohumeral osteoarthritis planned for anatomic shoulder arthroplasty at University Hospitals Leuven, Belgium
  • Complete patient informed consent
  • Pain free at the time of EOS imaging
  • Healthy adult volunteers with no history of shoulder pain or trauma
  • Physician-confirmed normal clinical evaluation and CT scan in healthy volunteers
  • Patients with glenohumeral osteoarthritis who had anatomic shoulder arthroplasty within the past 30 years and were revised for glenoid component loosening
  • At least one postoperative CT scan available for revised TSA patients
Not Eligible

You will not qualify if you...

  • Patients with postoperative shoulder stiffness, pain, instability, or pseudoparalysis

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

UZ Leuven

Leuven, Vlaams-Brabant, Belgium, 3000

Actively Recruiting

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Research Team

F

Filip Verhaegen

CONTACT

P

Philippe Debeer

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

3

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