Actively Recruiting
Glioblastoma Targeted Treatment Option Maximization by WGS
Led by UMC Utrecht · Updated on 2024-05-08
160
Participants Needed
1
Research Sites
153 weeks
Total Duration
On this page
Sponsors
U
UMC Utrecht
Lead Sponsor
A
Amsterdam University Medical Center
Collaborating Sponsor
AI-Summary
What this Trial Is About
In Dutch centers performing neurosurgery on and/or treating GBM, all recurrent GBM patients are discussed in local tumor boards and this setup will be used to effectively identify possible GLOW study candidates. 160 patients that will undergo re-resection in the GLOW study will be presented with WGS results leading to added treatment options.
CONDITIONS
Official Title
Glioblastoma Targeted Treatment Option Maximization by WGS
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Histopathologically confirmed IDH wild type glioblastoma, first recurrence after standard chemoradiation; suitable for standard-of-care re-resection
- Age 18 years or older
- Able and willing to give written informed consent
- Life expectancy greater than 3 months to allow adequate follow-up
- Karnofsky Performance Status (KPS) of 70 or higher
You will not qualify if you...
- Currently actively treated in another antitumor clinical trial (excluding DRUP and STELLAR studies)
- Any other clinically significant medical condition that makes participation undesirable or could jeopardize study compliance, including ongoing or active infection, significant uncontrolled hypertension, or severe psychiatric illness/social situations
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Haaglanden Medisch Centrum
The Hague, Netherlands
Actively Recruiting
Research Team
M
Mark Y van Opijnen
CONTACT
M
Marike Broekman
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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