Actively Recruiting
Global Collaborative Research on Establishing a Korean Cognitive Aging Cohort
Led by Korea University · Updated on 2026-03-20
180
Participants Needed
1
Research Sites
665 weeks
Total Duration
On this page
Sponsors
K
Korea University
Lead Sponsor
K
Korea University Anam Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this observational study is to learn how daily emotional stress affects cognitive function and inflammation in community-dwelling older adults aged 60 and older in Seoul, Republic of Korea. The main questions it aims to answer are: Does daily psychological stress measured in real-time affect short-term and long-term cognitive function in older adults? Do pro-inflammatory cytokines (such as CRP, IL-6, IL-10, and TNF-α) mediate the relationship between emotional stress and cognitive decline? How do social support and social isolation influence cognitive function and inflammatory biomarkers over time? Participants will: Complete baseline surveys assessing depression, cognitive function, and personal characteristics Use a smartphone app to answer brief surveys about their emotions, cognitive performance, and social interactions 1-6 times daily for two weeks Wear a Galaxy Watch to track sleep quality, heart rate, and physical activity Provide blood samples for inflammatory biomarker analysis Return for follow-up assessments at 6 months and 1 year This study is part of an international collaboration to establish a Korean cohort comparable to the U.S. Einstein Aging Study, with the aim of developing culturally tailored dementia prevention strategies.
CONDITIONS
Official Title
Global Collaborative Research on Establishing a Korean Cognitive Aging Cohort
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 60 or older residing in the Republic of Korea
- Samsung Galaxy smartphone users capable of using smartphone applications
- Sufficient cognitive ability to understand and follow research instructions (MMSE score of 21 or above)
- For individuals who do not meet the cognitive criteria, those who understand the study procedures and provide informed consent along with their legal guardian
You will not qualify if you...
- Diagnosis of dementia at baseline
- Severe visual or hearing impairments that prevent participation in psychological assessments
- Illiteracy that prevents participation in cognitive testing
- Less than 80% compliance with the 2-day preliminary EMA protocol (one additional attempt allowed after re-training)
- Current alcohol or substance abuse
- Inability to ambulate or psychiatric conditions that prevent survey participation
- Currently undergoing cancer treatment or received chemotherapy within the past 6 months
AI-Screening
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Trial Site Locations
Total: 1 location
1
Korea University
Seoul, Select One..., South Korea, 02841
Actively Recruiting
Research Team
S
Sunmi Song, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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