Actively Recruiting

All Genders
NCT05755867

Global PNH Patient Registry

Led by Aplastic Anemia and MDS International Foundation · Updated on 2025-02-20

500

Participants Needed

1

Research Sites

521 weeks

Total Duration

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Sponsors

A

Aplastic Anemia and MDS International Foundation

Lead Sponsor

N

National Organization for Rare Disorders

Collaborating Sponsor

AI-Summary

What this Trial Is About

The primary aim of the Global Paroxysmal Nocturnal Hemoglobinuria (PNH) Patient Registry is to conduct a prospectively-planned and efficient natural history study that will result in a more comprehensive understanding of the disease and its course and pace over time. Other registry objectives include the following: * Provide a convenient online platform for participants (or caregivers) to self-report cases of PNH. * Develop a communications registry within the Global PNH Patient registry (e.g., to notify patients of research studies and clinical trials). * Characterize and describe the Global PNH population as a whole, enhancing the understanding of disease prevalence and phenotype as well as the rate of progression of disease characteristics. * Assist the PNH community with the development of recommendations and standards of care. * Be a case-finding resource to be used for researchers who seek to study the pathophysiology of PNH, retrospectively collate intervention outcomes, and design prospective trials of novel treatments.

CONDITIONS

Official Title

Global PNH Patient Registry

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Individuals of any age with a confirmed diagnosis of PNH or diagnosis consistent with PNH
  • Willingness to provide informed consent (by participant or legally authorized representative)
  • Ability to access the internet periodically and comply with web-based study procedures
Not Eligible

You will not qualify if you...

  • Inability to read and understand English

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Aplastic Anemia and MDS International Foundation

Bethesda, Maryland, United States, 20814

Actively Recruiting

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Research Team

A

Alice Houk, MS

CONTACT

E

Elizabeth Kottke

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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