Actively Recruiting
A Global Study of the PETAL Consortium
Led by Massachusetts General Hospital · Updated on 2026-04-09
1200
Participants Needed
14
Research Sites
208 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this observational study is to correlate molecular alterations with outcomes including overall survival (OS), progression-free survival (PFS), response rates for patients with a new diagnosis, primary refractory or relapse, of mature T-cell and NK-cell neoplasms (TNKL). We hypothesize that machine learning can be leveraged to uncover distinct genetic vulnerabilities that underlie treatment response and resistance for patients with TNKL, thus moving towards personalized treatment solutions.
CONDITIONS
Official Title
A Global Study of the PETAL Consortium
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Untreated, relapsed, or refractory histologically confirmed mature T-cell or NK-cell neoplasm.
- Any subtype of peripheral T-cell lymphoma except T-cell large granular lymphocytic leukemia, cutaneous T-cell lymphoma (including mycosis fungoides and transformation), S�e9zary syndrome, and primary cutaneous CD30+ disorders.
You will not qualify if you...
- Precursor T/NK neoplasms, T-cell large granular lymphocytic leukemia, cutaneous T-cell lymphoma such as mycosis fungoides and transformation, S�e9zary syndrome, and primary cutaneous CD30+ disorders.
- Adults unable to consent.
- Infants, children, and teenagers.
- Pregnant women.
- Prisoners.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 14 locations
1
City of Hope
Duarte, California, United States, 91010
Actively Recruiting
2
University of Colorado
Denver, Colorado, United States, 80204
Actively Recruiting
3
Moffitt Cancer Center
Tampa, Florida, United States, 33612
Actively Recruiting
4
Massachusetts General Hospital
Boston, Massachusetts, United States, 02114
Actively Recruiting
5
Dana-Farber Cancer Institute
Boston, Massachusetts, United States, 02215
Actively Recruiting
6
Mayo Clinic
Rochester, Minnesota, United States, 55905
Actively Recruiting
7
Hackensack University Medical Center
Hackensack, New Jersey, United States, 07601
Actively Recruiting
8
OhioHealth
Columbus, Ohio, United States, 43214
Actively Recruiting
9
University of Pennsylvania
Philadelphia, Pennsylvania, United States, 19104
Actively Recruiting
10
University of Virginia
Charlottesville, Virginia, United States, 22903-4
Actively Recruiting
11
Royal Adelaide Hospital
Adelaide, South Australia, Australia, 5000
Actively Recruiting
12
Peter MacCallum Cancer Centre
Melbourne, Victoria, Australia, 3000
Actively Recruiting
13
Kyoto University
Kyoto, Japan, 606-8501
Actively Recruiting
14
University of Cape Town
Cape Town, South Africa, South Africa, 7700
Actively Recruiting
Research Team
S
Salvia Jain, MD
CONTACT
F
Forum Bhanushali
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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