Actively Recruiting

Age: 18Years - 80Years
All Genders
NCT06481826

Glofitamab in Chinese Patients With R/R DLBCL

Led by Peking Union Medical College Hospital · Updated on 2026-03-27

20

Participants Needed

1

Research Sites

260 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study will evaluate the safety and efficacy of glofitamab as a single agent in Chinese patients with relapsed or refractory (R/R) diffuse large B-cell lymphoma (DLBCL) who have failed two or more lines of systemic therapy.

CONDITIONS

Official Title

Glofitamab in Chinese Patients With R/R DLBCL

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Histologically-confirmed diffuse large B-cell lymphoma (DLBCL)
  • Relapsed or refractory disease after at least two prior systemic therapies
  • Presence of measurable disease
Not Eligible

You will not qualify if you...

  • Pregnancy or breastfeeding
  • Active infection or reactivation of a latent infection
  • Active autoimmune disease or immune deficiency
  • Severe organ failure: left ventricular ejection fraction below 40%, diffusing capacity of the lungs for carbon monoxide below 40%, estimated glomerular filtration rate below 30 ml/min, or bilirubin level three times above the upper limit of normal
  • Dependence on the study sponsor, investigator, or trial site

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Peking Union Medical College Hospital

Beijing, Beijing Municipality, China, 100730

Actively Recruiting

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Research Team

J

Jing Ruan

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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Glofitamab in Chinese Patients With R/R DLBCL | DecenTrialz