Actively Recruiting
GLOW Study: A Randomized Trial to Evaluate the Effects of Triple Support Protein on Glucose, Lifestyle, and Overall Well-being in Women
Led by University of North Carolina, Chapel Hill · Updated on 2026-04-13
40
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
Sponsors
U
University of North Carolina, Chapel Hill
Lead Sponsor
P
Perelel Inc.
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are evaluating whether taking a daily supplement of Triple Support Protein powder for 4 weeks can improve blood sugar control and overall well-being in healthy women aged 30 to 60 years. The study focuses on midlife women who may face hormonal changes affecting metabolism, sleep, and cognition. This randomized, double-blind, placebo-controlled trial compares the effects of a plant-based protein supplement containing creatine and fiber to a matched placebo. Participants will be randomly assigned to receive either the Triple Protein Support supplement or a non-caloric placebo, both taken once daily mixed with water for 4 weeks. The study includes an acute supervised dose followed by daily supplementation. Assessments include baseline and end-of-study body composition scans (DXA), fasting blood tests, standardized meal tests with 2-hour glucose and insulin measurements, and wearing a continuous glucose monitor during the last 14 days of the study. Throughout the study, participants will attend weekly check-ins and undergo detailed testing to monitor changes in post-meal glucose levels, insulin sensitivity, and lean body mass. Researchers will analyze these outcomes to understand how the supplement affects glucose control and metabolic health. The total participation duration is approximately 6 weeks, with safety and adherence closely monitored by the study team.
CONDITIONS
Brief Title
GLOW Study: Effects of Triple Protein in Women
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Females aged 30-60 years
- Body mass index (BMI) between 18.5 and 40 kg/m²
- Recreationally active with at least 30 minutes of moderate exercise per week
- Healthy and free from disease based on health history
- Willing to avoid caffeine, tobacco, and alcohol for 24 hours before testing days
You will not qualify if you...
- Currently taking whey protein supplements
- Pregnant or nursing
- Lactose intolerant
- Currently using creatine monohydrate
- Severe hearing or speech impairment or unable to speak English
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - 4 weeks
Participants take either the triple protein support supplement or a matched placebo daily for 4 weeks to evaluate effects on glucose, lifestyle, and well-being.
Weekly visits for check-ins and assessments, including baseline and end-of-study visits with DXA and blood sampling
Trial Site Locations
Total: 1 location
1
Department of Exercise and Sport Science, Applied Physiology Laboratory
Chapel Hill, North Carolina, United States, 27713
Actively Recruiting
Research Team
A
Abbie Smith-Ryan
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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