Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
Healthy Volunteers
NCT06468865

Glucose Monitoring in Treatment of Postprandial Hypoglycemia After Gastric Bypass Surgery

Led by Sykehuset i Vestfold HF · Updated on 2024-11-05

100

Participants Needed

1

Research Sites

111 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this clinical trial is to learn if continuous glucose monitoring works to treat postprandial hypoglycaemia in patients who have undergone gastric bypass surgery. The main question it aims to answer is: • Is continuous glucose monitoring superior to usual care for prevention of postprandial hypoglycaemia in patients with verified postprandial hypoglycaemia after gastric bypass surgery? Researchers will compare continuous glucose monitoring to usual care to see if continuous glucose monitoring works to treat postprandial hypoglycaemia. Participants will: * Use a continuous glucose monitor for 6 weeks or use no continuous glucose monitor for 5 weeks and wear a blinded continuous glucose monitor for 1 week. * Visit the clinic 2-3 times and have 2-3 phone consultations. * Register symptoms of hypoglycaemia, answer questionnaires, undergo a 24-hour dietary recall interview conducted by a registered dietitian, measure weight and body composition and take blood samples.

CONDITIONS

Official Title

Glucose Monitoring in Treatment of Postprandial Hypoglycemia After Gastric Bypass Surgery

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Gastric bypass surgery at least 1 year ago
  • Age 18 years or older
  • Symptoms of postprandial hypoglycemia with capillary glucose below 3.0 mmol/L within 1 to 4 hours after meals
Not Eligible

You will not qualify if you...

  • Unable to give informed consent
  • Severe mental or psychiatric conditions reducing compliance
  • Use of insulin or sulfonylureas
  • Use of systemic corticosteroids
  • Primary or secondary adrenal insufficiency
  • Insulinoma
  • Severe heart, lung, liver, or kidney disease, cancer, malnutrition, or other conditions causing fragility
  • Previous bariatric revisional surgery
  • Drug or alcohol abuse
  • Pregnancy
  • Use of acarbose or octreotide for postprandial hypoglycemia
  • Current use of a continuous glucose monitor

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

1Department of Endocrinology, Obesity and Nutrition, Vestfold Hospital Trust

Tønsberg, Vestfold, Norway, 3103

Actively Recruiting

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Research Team

H

Heidi Borgeraas, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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