Glucose Monitoring Study in Women Over 18 With Polycystic Ovary Syndrome Using New Sensor Technology

What this Trial Is About

Polycystic ovary syndrome PCOS is a common condition linked to metabolic problems, including insulin resistance and a higher risk of developing type 2 diabetes. PCOS has four different phenotypes A-D, and some may have less risk of insulin resistance. This research aims to study glucose levels continuously to see how glucose profiles differ among these PCOS phenotypes using new monitoring technology. Participants in this study will use a Free-style Libre Pro sensor device to continuously monitor glucose levels for 14 days. The study compares four PCOS phenotypes based on combinations of symptoms such as irregular menstrual cycles, hyperandrogenism, and ovarian morphology or AMH levels. Additionally, an Age Reader device will analyze glycation end products related to glucose control. Women in the trial will be monitored over two weeks, with continuous glucose data collected through the sensor. Researchers will assess time spent within glucose target ranges, average blood sugar levels, variability, and presence of low blood sugar. Other tests include HbA1C, oral glucose tolerance, insulin resistance evaluation, and glycation product measurement. The study is non-randomized and open-label, with participation starting in January 2026 and ending in July 2027.

Glucose Profiles in Women With Polycystic Ovary Syndrome