Actively Recruiting
GLycaemic Outcomes With Whey Protein in ageING
Led by University of Birmingham · Updated on 2025-12-16
32
Participants Needed
2
Research Sites
52 weeks
Total Duration
On this page
Sponsors
U
University of Birmingham
Lead Sponsor
N
Newcastle University
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this placebo-controlled, partial crossover design study is to identify the impact of consuming whey protein before meals on free-living glucose control in older adults living with type 2 diabetes. The primary specific objective is to determine the effect of a thrice daily whey protein pre-meal supplementation at two doses, on glucose excursions over a 7-day free-living period in adults aged 75-90 years of age, living with type 2 diabetes, compared with a non-protein placebo. Participants will consume the whey protein and placebo for 7 days each, before each meal. All participants will consume the placebo and one of two doses of whey protein, in a randomised order.
CONDITIONS
Official Title
GLycaemic Outcomes With Whey Protein in ageING
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male or female
- 75 to 90 years old
- Diagnosed with type 2 diabetes confirmed by HbA1c >6.5%
- Stable body mass with BMI ≤40 kg/m2
- Generally healthy based on a health questionnaire
- Some remaining beta-cell activity confirmed by urine test
- Normal or moderately increased albuminuria below 300 mg/g
- Normal to moderately decreased kidney filtration rate above 45 ml/min/1.732
- Able and willing to attend five visits including induction, testing, and check-ups
You will not qualify if you...
- Younger than 75 or older than 90 years
- Currently using fast-acting insulin therapy such as Humalog
- Uncontrolled diabetes with HbA1c >10% or 85 mmol/mol
- Currently using GLP-1 therapy
- Habitual smoker or vape user
- Vegan diet
- Lactose or dairy intolerance
- Coeliac disease or gluten intolerance
- History of gastrointestinal disease
- Experienced severe low or high blood sugar events requiring treatment in past 12 months
- Recent ischemic stroke within 3 months
- Use of blood thinners like warfarin or rivaroxaban
- Unable or unwilling to follow study procedures as judged by research team
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Trial Site Locations
Total: 2 locations
1
School of Sport, Exercise and Rehabilitation Sciences, University of Birmingham
Birmingham, West Midlands, United Kingdom, B15 2TT
Enrolling by Invitation
2
Heartlands Hospital
Birmingham, United Kingdom
Actively Recruiting
Research Team
L
Leigh Breen, PhD
CONTACT
M
Marie Korzepa, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
BASIC_SCIENCE
Number of Arms
3
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