Actively Recruiting
Glycocalyx and Oxidative Stress in Endothelial Function (Part 1)
Led by Josip Juraj Strossmayer University of Osijek · Updated on 2026-03-02
105
Participants Needed
1
Research Sites
208 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The primary research objective of the project is to determine the role of eGC in microvascular reactivity in CKD (cross-sectional study 1). The main objective of the project is to increase the excellence and interdisciplinarity of scientific work at MEFOS by connecting researchers from different scientific fields, improving conditions and resources for scientific work, and increasing international cooperation, in line with strategic objective 1: raising scientific excellence. The results of the project could provide pathophysiological insight into the development and maintenance of endothelial dysfunction in CKD, as well as identify new biomarkers for CKD.
CONDITIONS
Official Title
Glycocalyx and Oxidative Stress in Endothelial Function (Part 1)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with chronic kidney disease caused by high blood pressure (grades 1-2 and 3-5; eGFR CKD-EPI \u2265 90 ml/min/1.73 m\u00b2, i.e. < 60 mL/min/1.73 m2), who are non-diabetic and non-smokers
- Patients with hypertension without kidney damage (eGFR CKD-EPI >90 mL/min/1.73 m2), who are non-diabetic and non-smokers
- Healthy volunteer subjects as controls
You will not qualify if you...
- Kidney disease caused by any condition other than hypertension
- Endocrine, autoimmune, or inflammatory diseases that could affect kidney function
- Smoking
- Diabetes
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Osijek University Hospital
Osijek, Croatia, 31000
Actively Recruiting
Research Team
I
Ines Drenjančević, MD, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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