Actively Recruiting

Age: 18Years +
All Genders
NCT07451873

Glycocalyx and Oxidative Stress in Endothelial Function (Part 2)

Led by Josip Juraj Strossmayer University of Osijek · Updated on 2026-03-09

35

Participants Needed

1

Research Sites

208 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The primary research objective of the project is to determine the role of eGC in microvascular reactivity in patients with coronary heart disease (CHD) before and after bypass grafting (cross-sectional study 2).The main objective of the project is to increase the excellence and interdisciplinarity of scientific work at MEFOS by connecting researchers from different scientific fields, improving conditions and resources for scientific work, and increasing international cooperation, in line with strategic objective 1: raising scientific excellence. The results of the project could provide pathophysiological insight into the development and maintenance of endothelial dysfunction in CVD, as well as identify new biomarkers for CVD.

CONDITIONS

Official Title

Glycocalyx and Oxidative Stress in Endothelial Function (Part 2)

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult patients of both sexes over 18 years of age
  • Caucasian
  • Undergoing elective coronary artery bypass grafting (CABG)
  • Provided written informed consent
Not Eligible

You will not qualify if you...

  • Emergency surgery
  • Sepsis or severe systemic inflammation before surgery
  • Severe renal or hepatic insufficiency
  • Immunosuppression
  • Serious comorbidities such as active cancer
  • Therapies that could affect oxidative stress, for example, high doses of corticosteroids

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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2
3
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Trial Site Locations

Total: 1 location

1

Osijek University Hospital

Osijek, Croatia, 31000

Actively Recruiting

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Research Team

I

Ines Drenjančević, MD, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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Glycocalyx and Oxidative Stress in Endothelial Function (Part 2) | DecenTrialz