Actively Recruiting

Phase Not Applicable
Age: 45Years - 65Years
All Genders
Healthy Volunteers
NCT05980052

Goal Setting to Promote Physical Activity Adherence in Midlife Adults

Led by Arizona State University · Updated on 2025-07-17

144

Participants Needed

1

Research Sites

180 weeks

Total Duration

On this page

Sponsors

A

Arizona State University

Lead Sponsor

N

National Institute on Aging (NIA)

Collaborating Sponsor

AI-Summary

What this Trial Is About

Engaging in regular physical activity during midlife is a key lifestyle behavior associated with reduced risk for Alzheimer's disease and related dementias (AD/ADRD). Yet nearly half of midlife adults (48%) do not meet national physical activity guidelines. The purpose of this mechanistic trial is to identify effective goal setting techniques to enhance psychosocial processes of self-regulation for the successful promotion of PA and adherence to national PA guidelines among midlife adults, with the long-term goal of reducing AD/ADRD risk

CONDITIONS

Official Title

Goal Setting to Promote Physical Activity Adherence in Midlife Adults

Who Can Participate

Age: 45Years - 65Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Aged 45 to 65 years
  • Body mass index (BMI) between 30 kg/m2 and 50 kg/m2
  • Weigh at least 110 pounds
  • Engaging in 60 minutes or less of self-reported moderate-to-vigorous physical activity at screening
  • Own a smartphone with iOS or Android operating system
Not Eligible

You will not qualify if you...

  • Answering yes to any Physical Activity Readiness Questionnaire (PAR-Q) item without a physician's note
  • Resting blood pressure greater than 200/110 mmHg without a physician's note
  • Pregnant or planning to become pregnant in the next 8 months (Phase 1) or 12 months (Phase 2)
  • Planning to move away from metropolitan Phoenix, Arizona in the next 8 months (Phase 1) or 12 months (Phase 2)
  • Participating in another physical activity, nutrition, or weight loss program currently or during the intervention
  • Diagnosed with mild cognitive impairment (MCI) or scoring below cutoffs on the Montreal Cognitive Assessment (MoCA)
  • Previously prescribed any of the five approved Alzheimer's medications
  • Scoring 16 or higher on the Center for Epidemiological Studies-Depression Scale (CES-D)
  • Currently diagnosed with major depression
  • Taking two or more antidepressant drugs
  • History of stroke
  • Being incarcerated (prisoner)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Arizona State University

Phoenix, Arizona, United States, 85004

Actively Recruiting

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Research Team

R

Rodney Joseph, PhD

CONTACT

M

Molly Maxfield, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

4

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Goal Setting to Promote Physical Activity Adherence in Midlife Adults | DecenTrialz