Actively Recruiting
Golidocitinib Combined With Mitoxantrone Hydrochloride Liposome or Chidamide in the Treatment of Relapsed or Refractory Peripheral T-cell Lymphoma
Led by Sun Yat-sen University · Updated on 2025-12-31
101
Participants Needed
1
Research Sites
205 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This is a prospective, multicenter, open-label, phase Ib/II clinical study to evaluate the safety and efficacy of golidocitinib combined with mitoxantrone hydrochloride liposome or chidamide in the treatment of relapsed or refractory peripheral T-cell lymphoma
CONDITIONS
Official Title
Golidocitinib Combined With Mitoxantrone Hydrochloride Liposome or Chidamide in the Treatment of Relapsed or Refractory Peripheral T-cell Lymphoma
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Voluntarily agree to participate and sign informed consent
- Diagnosed with peripheral T-cell lymphoma per 2022 WHO classification based on pathology
- Have at least one measurable or evaluable lesion per Lugano 2014 criteria
- Age 18 years or older
- Expected survival longer than 12 weeks
- ECOG performance status between 0 and 2
- Adequate organ and bone marrow function
You will not qualify if you...
- Presence of hemophagocytic lymphohistiocytosis (HLH)
- Lymphoma involvement in the central nervous system or meninges
- Active infections
- Uncontrolled cardiac symptoms or diseases
- Current use of strong CYP3A inducers or inhibitors that cannot be stopped at least one week before treatment
- Current use of vitamin K antagonists, antiplatelet agents, or anticoagulants that cannot be stopped at least one week before treatment
- History of HIV infection or AIDS
- Mental disorders or inability to provide informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Sun Yat-sen Universitiy Cancer Center, Sun Yat-Sen University
Guangzhou, Guangdong, China
Actively Recruiting
Research Team
Q
Qingqing Cai
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here