Actively Recruiting
GOS and the Management of Hyperuricemia
Led by Sun Yat-sen University · Updated on 2024-10-08
70
Participants Needed
1
Research Sites
76 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Hyperuricemia is a major risk factor for many chronic diesease. Recently, gut mcirobiota has been identified as a novel therapeutic target for hyperuricemia. Both annimal studies and pilot human trials have demonstrated that administration of prebiotics help delay the progression of hyperuricemia throuh several mechanisms. This trial aims to examine the protective effects and potential mechanisms of galactooligosaccharide on hyperuricemia in clinical trials.
CONDITIONS
Official Title
GOS and the Management of Hyperuricemia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Local residents aged between 18-80 years old
- Stable weight with less than 5% change over the past 3 months
- Fasting uric acid above 420 umol/L for males and above 360 umol/L for females on two separate days
- Not currently taking uric acid lowering drugs or have stopped them for over 4 weeks before recruitment
- No use of antibiotics, prebiotics, or probiotics that could affect uric acid metabolism or gut microbiota within 4 weeks before recruitment
You will not qualify if you...
- Acute illness or signs of any acute or chronic inflammatory or infectious diseases
- Participation in regular diet programs more than twice per week in the last 3 months before recruitment
- Mental illness preventing understanding of the study's nature, scope, and possible consequences
- Women of childbearing age who are pregnant, breastfeeding, or planning pregnancy
- Patients who had surgery within the past 6 months or have planned surgery during the trial period
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Sun Yat-Sen University
Guangzhou, Guangdong, China, 510080
Actively Recruiting
Research Team
Y
Yan Liu, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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