Actively Recruiting
GPC3 Targeted Fluorescence Image Guided Surgery of Hepatocellular Carcinoma
Led by Chinese Academy of Sciences · Updated on 2023-08-30
60
Participants Needed
2
Research Sites
276 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study is to evaluate whether intraoperative fluorescence imaging targeting GPC3 can aid improve the surgical accuracy of hepatocellular carcinoma. The main purposes of this study include: ① To raise the detection rate of hepatocellular carcinoma intraoperatively using the novel NIR-II fluorescence molecular imaging and the GPC-3 targeted fluorophore. ② To validate the safety and effectiveness of the designed GPC-3 targeted fluorophore for clinical application.
CONDITIONS
Official Title
GPC3 Targeted Fluorescence Image Guided Surgery of Hepatocellular Carcinoma
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients diagnosed with hepatocellular carcinoma
- Planned to receive hepatectomy (liver surgery)
- Liver function classified as Child-Pugh A or B
- Preoperative confirmation of high GPC-3 expression
- Age between 18 and 75 years with expected lifetime longer than 6 months
- Approved and able to sign informed consent
You will not qualify if you...
- Allergy to IRDye800
- Participation in other clinical trials within the past 3 months
- Presence of another malignant tumor
- Poor heart, lung, kidney, or other organ function
- Unable to tolerate hepatectomy
- Considered inappropriate for inclusion by the researchers
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Zhuhai People's Hospital
Zhuhai, Guangdong, China
Actively Recruiting
2
The Affiliated Hospital of Southwest Medical University
Luzhou, Sichuan, China
Actively Recruiting
Research Team
Z
Zeyu Zhang, Ph.D.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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