Actively Recruiting
GR1803 Injection in Patients With Relapsed/Refractory Multiple Myeloma
Led by Genrix (Shanghai) Biopharmaceutical Co., Ltd. · Updated on 2025-04-27
116
Participants Needed
1
Research Sites
152 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
All subjects will receive GR1803 injection until intolerable toxicity or investigator-assessed disease progression occurs (except in cases of disease progression due to discontinuation of the drug as a result of an adverse event) or until the subject has been administered the drug for 2 years or until the subject withdraws consent or until the investigator determines that the subject needs to be discontinued.
CONDITIONS
Official Title
GR1803 Injection in Patients With Relapsed/Refractory Multiple Myeloma
Who Can Participate
Eligibility Criteria
You may qualify if you...
- ECOG performance status score of 0 to 2
- Age 18 years or older
- Multiple myeloma measurable by central lab tests: serum monoclonal protein (M-protein) level at least 0.5 g/dL or urine M-protein level at least 200 mg/24 hours
- For light chain multiple myeloma without measurable serum or urine disease: serum immunoglobulin free light chain (FLC) at least 10 mg/dL with abnormal kappa/lambda FLC ratio
You will not qualify if you...
- Prior treatment with any BCMA-targeted therapy
- Known active central nervous system involvement or meningeal signs of multiple myeloma
- Known allergies, hypersensitivity, or intolerance to teclistamab or its excipients
- Diagnosis of plasma cell leukemia, Waldenström's macroglobulinemia, POEMS syndrome, or primary amyloid light-chain amyloidosis
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
he First Affiliated Hospital, Zhejiang University School of Medicine
Hangzhou, Zhejiang, China, 310003
Actively Recruiting
Research Team
J
Jie Jin, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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