Comparing Gradual and Intermittent Tourniquet Release in Controlled Hypertensive Adults During Upper Limb Orthopedic Surgery

What this Trial Is About

Researchers are comparing two methods of releasing a tourniquet and their effects on blood pressure and acid-base balance in hypertensive patients undergoing upper limb orthopedic surgeries under general anesthesia. This study focuses on patients with controlled hypertension and aims to assess clinical impacts during surgery. Participants will receive general anesthesia with specific drugs and mechanical ventilation adjusted to maintain proper respiratory parameters. The tourniquet will be applied to the arm with pressure set above the patients systolic blood pressure. After surgery, the tourniquet will be deflated either gradually over three minutes or intermittently with cycles of deflation and reinflation, depending on random assignment and surgery duration. During the study, patients hemodynamics and laboratory tests including acid-base status, lactate, and potassium levels will be monitored. The anesthesiologist collecting data will be blinded to the deflation method used. The primary outcome is mean arterial pressure measured five minutes after deflation. Monitoring and assessments occur around surgery, with total participation lasting for the surgery and immediate postoperative period as described.

Gradual Versus Intermittent Release of Tourniquet Effect on MAP in Hypertensive Patients Undergoing Upper Limb Orthopedic Surgeries