+1 877 705 191424 / 7
HIPAA Compliant
ISO 27001 Certified

Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
ID05972876

Effect of Blood Flow Restriction Training Versus Resistance Training on ACL Graft Maturity After Bone-Patellar Tendon-Bone Reconstruction

Led by Zuyderland Medisch Centrum · Updated on 2025-02-04

46

Participants Needed

1

Research Sites

52 weeks

Total Duration

AI-Summary

What this Trial Is About

Researchers are evaluating the effects of low-load blood flow restriction training LL-BFRT compared to heavy-load resistance training HLRT on graft maturity after anterior cruciate ligament ACL reconstruction using a bone-patellar tendon-bone graft. The study aims to understand whether LL-BFRT offers benefits or risks during rehabilitation by measuring MRI-based graft maturity as well as other factors like knee stability, range of motion, muscle strength, and patient satisfaction. Participants will be randomly assigned to one of two groups. The LL-BFRT group will perform biweekly strength training for 12 weeks starting two weeks after surgery, using a specialized tourniquet system to restrict blood flow during exercises such as leg press, leg extension, deadlift, and squats at 30% of their one-repetition maximum. The HLRT resistance training group will also train biweekly for 12 weeks, performing similar exercises but with heavier loads up to 70% of their one-repetition maximum without blood flow restriction. During the study, participants will be assessed at three and nine months after surgery with MRI scans to measure graft maturity and other evaluations including knee range of motion, stability, pain, function, muscle strength, and return to pre-injury sports level. Safety and feasibility of the rehabilitation methods will be monitored throughout. The total participation spans at least nine months to capture the main outcomes and recovery progress.

CONDITIONS

Brief Title

Graft Maturity After Blood Flow Restriction Training in ACL Reconstruction

Research Team

J

Jasper Most, PhD

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here