Actively Recruiting
Graves' Disease Remission Study: MycoMeth Combo
Led by The First Affiliated Hospital of Xiamen University · Updated on 2024-02-28
205
Participants Needed
1
Research Sites
155 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
A randomized study to evaluate the efficacy and safety of combining mycophenolate mofetil with methimazole in patients with newly diagnosed Graves' disease.
CONDITIONS
Official Title
Graves' Disease Remission Study: MycoMeth Combo
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged 18 to 60 years.
- Newly diagnosed with Graves' disease.
You will not qualify if you...
- Previously treated for Graves' disease or experienced relapse.
- Hyperthyroidism caused by other conditions such as toxic multinodular goiter, toxic thyroid adenoma, Hashimoto's thyroiditis, subacute thyroiditis, or iodine-induced hyperthyroidism.
- Needing treatment for moderate to severe thyroid eye disease at enrollment.
- Hyperthyroidism requiring surgery due to thyroid cancer.
- Severe liver or kidney dysfunction (ALT or AST more than 3 times normal, creatinine above 135 mol/L for males or 110 mol/L for females).
- Leukopenia (white blood cell count below 3.0×10^9/L).
- Severe heart failure (New York Heart Association class III or IV).
- Chronic or severe infections like pulmonary tuberculosis or hepatitis B.
- Pregnant, breastfeeding, planning pregnancy soon, or unable to use contraception during the trial.
- Participation in other clinical studies currently or previously.
- Unwilling or unable to comply with follow-up or participate in the study.
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Xiao Fangsen
Xiamen, Fujian, China, 361003
Actively Recruiting
Research Team
F
Fangsen Xiao, MD
CONTACT
L
Liyin Wang, MM
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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