Actively Recruiting

Phase 1
Phase 2
Age: 18Years - 80Years
All Genders
NCT06747676

GRAViceptive NEGlect Treatment in Acute Stroke Using Targeted Cranial ELECTrotherapy

Led by University of Sao Paulo · Updated on 2025-02-03

28

Participants Needed

2

Research Sites

53 weeks

Total Duration

On this page

Sponsors

U

University of Sao Paulo

Lead Sponsor

T

Thomas Jefferson University

Collaborating Sponsor

AI-Summary

What this Trial Is About

We aim to determine if targeted high-definition transcranial direct current stimulation (HD-tDCS) can safely correct errors in visual verticality perception in patients after stroke affecting either hemisphere.

CONDITIONS

Official Title

GRAViceptive NEGlect Treatment in Acute Stroke Using Targeted Cranial ELECTrotherapy

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Supratentorial ischemic stroke diagnosed by neuroimaging and clinical analysis
  • Clinically stable with stable vital signs for 24 hours and no recent chest pain or significant arrhythmia
  • Normal or corrected-to-normal vision
  • No previous experience with HD-tDCS
  • Ability to provide informed consent (patient or legal representative)
  • Ability to comply with the intervention and assessment schedule
  • Presence of visual verticality misperception
Not Eligible

You will not qualify if you...

  • Migraine
  • Pregnancy
  • Pacemakers
  • Seizures
  • Claustrophobia
  • Transient ischemic attack
  • Other neurological disorders
  • Psychiatric disorders
  • Sensitive scalp or prior brain surgery
  • Severe carotid atherosclerotic disease (stenosis ≥ 70%)
  • Presence of metal implants, cardiac pacemakers, or claustrophobia
  • Diagnosis of COVID-19 or other infectious disease requiring isolation
  • Uncontrolled medical problems such as terminal cancer or kidney disease
  • Left-handed or mixed-handed individuals
  • Peripheral vestibular deficits observed in screening tests
  • Prior musculoskeletal disorders affecting alignment and balance (e.g., moderate to severe scoliosis, torticollis)
  • Cognitive dysfunction with Mini-Mental State Examination score below 23
  • Global or Wernicke's aphasia

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Ribeirão Preto Medical School, University of São Paulo

Ribeirão Preto, São Paulo, Brazil, 14015160

Actively Recruiting

2

University of São Paulo, Ribeirão Preto Medical School

Ribeirão Preto, São Paulo, Brazil, 14049-900

Not Yet Recruiting

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Research Team

T

Taiza G. S. Edwards, PhD

CONTACT

L

Lizanilda Albuquerque, BSc

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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GRAViceptive NEGlect Treatment in Acute Stroke Using Targeted Cranial ELECTrotherapy | DecenTrialz