Actively Recruiting
Greater Houston Area Pediatric Bipolar Registry
Led by The University of Texas Health Science Center, Houston · Updated on 2026-02-18
1000
Participants Needed
1
Research Sites
1252 weeks
Total Duration
On this page
Sponsors
T
The University of Texas Health Science Center, Houston
Lead Sponsor
J
John S. Dunn Foundation
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of this study is to perform a comprehensive research assessment of children and adolescents who meet The Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-V) criteria for Bipolar Disorder (BD) , offspring of a parent with BD, and healthy controls (HC), to obtain blood samples and saliva samples from each subject to allow the evaluation for BD biomarkers and genetic information, to notify participants about future research studies they may qualify for , to recommend follow-up with an outpatient provider if needed and to use magnetic resonance imaging (MRI) (structural MRI and diffusion tensor imaging) to investigate brain structures and relevant pathways associated with mood and behavioral regulation, conversion from softer forms of the BD spectrum (BD-NOS) to harder forms (BD-I and BD-II) and possible early identification.
CONDITIONS
Official Title
Greater Houston Area Pediatric Bipolar Registry
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Participants aged 6 to 17 years
- For bipolar patients: meet DSM-V criteria for BD type I, BD type II, or BD NOS as determined by the MINI Kid interview
- For offspring: at least one parent diagnosed with BD type I, BD type II, or BD NOS confirmed by MINI Adult interview
- Any current mood state in bipolar subjects
You will not qualify if you...
- Autism Spectrum Disorder (ASD)
- Intellectual Developmental Disorder
- Severe neurological disorders affecting cognition (e.g., epilepsy, traumatic brain injury, tubular sclerosis)
- Schizophrenia
- Uncontrolled or severe medical problems as judged by the investigator
- For offspring: parents with history of brain diseases such as seizures, stroke, meningitis, encephalitis, dementia, or other degenerative brain diseases
- For healthy controls: any psychiatric diagnosis or family history of Bipolar Disorder, Psychotic Disorder, Schizophrenia, Schizoaffective disorder, or neurological conditions in first-degree relatives
- Mental retardation or intellectual disability
- Exclusion criteria apply at annual visits as well
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
The University of Texas Health Science Center at Houston
Houston, Texas, United States, 77479
Actively Recruiting
Research Team
J
Jair C Soares, M.D. PhD
CONTACT
C
Courtney Vecera
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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