Actively Recruiting

Phase Not Applicable
Age: 45Years - 65Years
All Genders
Healthy Volunteers
NCT06123182

Guided Episodic Future Thinking to Increase Physical Activity Adherence and Promote Healthy Brain Aging

Led by University of Kansas Medical Center · Updated on 2026-03-27

160

Participants Needed

1

Research Sites

166 weeks

Total Duration

On this page

Sponsors

U

University of Kansas Medical Center

Lead Sponsor

N

National Institute on Aging (NIA)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this behavioral clinical trial is to learn how to increase physical activity in mid-life adults. Specifically, can guided imagery that includes creating mental pictures increase excitement about working out. Participants will be asked to complete testing at the beginning of the study, following 6-weeks of an in-person exercise program, and 6-weeks after finishing the exercise program. Testing will include an exercise test, MRI, questionnaires, computer tasks, and a blood draw.

CONDITIONS

Official Title

Guided Episodic Future Thinking to Increase Physical Activity Adherence and Promote Healthy Brain Aging

Who Can Participate

Age: 45Years - 65Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Speak English
  • Have access to reliable communication devices like a telephone, cell phone, or computer
  • Have normal or corrected vision and hearing
  • Be able to walk without assistive devices
  • Be physically underactive
  • Be able to give informed consent
  • Be able to exercise continuously on a recumbent stepper for 4 minutes at 25 watts or more and have no safety or aerobic exercise contraindications
  • Be able to communicate with investigators, follow 2-step commands, and answer consent questions correctly
  • Have stable blood pressure and statin medication doses for at least 30 days
  • Be willing and able to safely enter an MRI scanner and attempt the scan
  • Be willing and able to have a blood draw
Not Eligible

You will not qualify if you...

  • Have arrhythmias or recent acute cardiac events
  • Be at risk due to magnetic field safety concerns
  • Have any neurological or psychiatric disorder except depression or anxiety (including PTSD)
  • Have a history of seizures or head trauma affecting MRI data quality

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Kansas Medical Center

Kansas City, Kansas, United States, 66160

Actively Recruiting

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Research Team

M

Morgan Brucks

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

FACTORIAL

Primary Purpose

PREVENTION

Number of Arms

4

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