Actively Recruiting

Age: 18Years +
All Genders
NCT06637657

Guided Optimisation of Long-term Disease rEduction in secoNdary Prevention of CVD

Led by Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) · Updated on 2024-10-15

5586

Participants Needed

1

Research Sites

233 weeks

Total Duration

On this page

Sponsors

A

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Lead Sponsor

D

Dutch Network for Cardiovascular Research (WCN), Utrecht

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this observational study is to evaluate the implementation of a 'first-time-right' pharmacological treatment strategy in patients hospitalized with coronary artery disease. The main question it aims to answer is: Does early (immediately post-event) initiation of a full set of guideline-based, individualized, preventive medication lead to reductions in cardiovascular events compared to current practice (incremental titration strategies)? Researchers will compare the 'first-time-right' strategy group to the current practice group to see if there are improvements in major adverse cardiac and cerebrovascular events (MACE) at 36 months. Participants will: * Receive either the 'first-time-right' strategy or current practice for secondary prevention. * Be monitored (data collection) through routine clinical visits at baseline, 8 weeks, 12, and additional telephone contacts at 24, and 36 months after discharge. * Complete online questionnaires at hospitalization, 8 weeks, 12, 24, and 36 months after discharge.

CONDITIONS

Official Title

Guided Optimisation of Long-term Disease rEduction in secoNdary Prevention of CVD

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Over 18 years of age
  • Recent coronary event such as acute coronary syndrome or coronary revascularization
  • Able to provide informed consent
Not Eligible

You will not qualify if you...

  • Currently pregnant or breastfeeding or planning pregnancy soon
  • Receiving dialysis treatment

AI-Screening

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Trial Site Locations

Total: 1 location

1

Amsterdam UMC

Amsterdam, Netherlands

Actively Recruiting

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Research Team

M

Manon van den Bogaart, drs.

CONTACT

M

Marjolein Snaterse, dr.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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