Actively Recruiting
The Gut-Brain Axis During Neurorehabilitation; Prebiotic Treatment to Alter the Gut Microbiome and Neurologic Symptoms
Led by The University of Texas Medical Branch, Galveston · Updated on 2025-12-19
130
Participants Needed
1
Research Sites
186 weeks
Total Duration
On this page
Sponsors
T
The University of Texas Medical Branch, Galveston
Lead Sponsor
M
Moody Neurorehabilitation Institute
Collaborating Sponsor
AI-Summary
What this Trial Is About
The aim of this study is to characterize the microbiome of patients undergoing post-acute residential neurorehabilitation compared to community controls and to determine if a dietary fiber, Inulin, can create a shift in the microbiome leading to changes in fatigue and cognition.
CONDITIONS
Official Title
The Gut-Brain Axis During Neurorehabilitation; Prebiotic Treatment to Alter the Gut Microbiome and Neurologic Symptoms
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Ages 18 and above
- Admitted to Moody Neurorehabilitation Institute for care
- Less than 6 months post-injury
- English speaking
- Must be able to eat and drink by mouth
- Willing and able to comply with study procedures
- Willing and able to provide consent (with LAR if needed)
- Ages 18 and above
- Have a family member who is admitted to Moody Neurorehabilitation Institute for care OR is working at Moody Neurorehabilitation Institute
- English speaking
- Willing and able to comply with study procedures
- Willing and able to provide consent
- FACs score 64 50
You will not qualify if you...
- Significant heart, liver, kidney, blood or respiratory disease
- HIV, Hepatitis B or Hepatitis C
- Pregnancy or becoming pregnant during the study
- History of inflammatory bowel disease
- History of celiac disease
- Active diverticular disease
- Known allergy to study agent
- Any medical condition that, in the opinion of the investigator, would place the subject at increased risk for participation
- Trauma to head in last 6 months
- Stroke in last 6 months
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Texas Medical Branch
Galveston, Texas, United States, 77555
Actively Recruiting
Research Team
K
Kate Randolph, BS
CONTACT
C
Christopher Danesi, MS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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