Actively Recruiting
Haemdall: Developing a Quantitative MRI Biomarker of Infratentorial Superficial Siderosis of the Central Nervous System
Led by Perspectum · Updated on 2025-08-20
50
Participants Needed
1
Research Sites
72 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Haemdall: Using Medical Imaging to measure Brain Iron in Superficial Siderosis. This study is looking at a new way of using MRI scans to potentially measure the amount of iron on the surface of the brain. Iron build up in the brain is linked to how superficial siderosis develops. The study will also aim to see if there is a connection between the amount of iron in the brain and common superficial siderosis symptoms. Clinical tests will be used to measure symptoms including tests to measure your hearing, walking \& balance and participants' ability to remember, think and understand.
CONDITIONS
Official Title
Haemdall: Developing a Quantitative MRI Biomarker of Infratentorial Superficial Siderosis of the Central Nervous System
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18 years or older with a confirmed diagnosis of superficial siderosis
- Ability to communicate in English and understand the study requirements
- Willing and able to provide informed consent
- Adults aged 18 years or older without neurological disorders (healthy cohort)
- Ability to communicate in English and understand the study requirements (healthy cohort)
- Willing and able to provide informed consent (healthy cohort)
You will not qualify if you...
- Any contraindication to MRI such as pregnancy, extensive tattoos, pacemaker, shrapnel injury, unfixed metallic implants, metallic fragments, severe claustrophobia, or cochlear implants
- Significant disease or disorder that may put the participant at risk or affect study results
- Inability to understand study information or provide informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Perspectum
Oxford, United Kingdom, OX4 2LL
Actively Recruiting
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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