Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT05746884

Haemostatic Gel Prophylaxis for Post Duodenal Endoscopic Resection Bleeding

Led by GCS Ramsay Santé pour l'Enseignement et la Recherche · Updated on 2026-02-27

234

Participants Needed

1

Research Sites

266 weeks

Total Duration

On this page

Sponsors

G

GCS Ramsay Santé pour l'Enseignement et la Recherche

Lead Sponsor

E

Euraxi Pharma

Collaborating Sponsor

AI-Summary

What this Trial Is About

The purpose of this study is to test whether prophylactic application of haemostatic gel will reduce the rate of clinically significant bleeding requiring intervention (such as blood transfusion, admission to hospital, other blood products) following endoscopic resection of advanced duodenal neoplasia compared to standard therapy.

CONDITIONS

Official Title

Haemostatic Gel Prophylaxis for Post Duodenal Endoscopic Resection Bleeding

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Single ampullary lesion 10mm or larger
  • Up to 2 duodenal lesions
  • Lesion size 15mm or less
  • Resection by hot ampullectomy or hot endoscopic mucosal resection
  • Lesion morphology 0-Is, 0-IIa/b/c or combination, or submucosal lesions
Not Eligible

You will not qualify if you...

  • Unable to provide informed consent (including cognitive impairment)
  • Pregnant or breastfeeding women
  • Allergy to PuraStat®
  • Cold mucosal endoscopic resection
  • Under guardianship, curatorship, or deprived of liberty
  • Currently participating or recently excluded from another clinical trial
  • Not covered by a social security scheme

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Hôpital Privé Jean Mermoz

Lyon, France

Actively Recruiting

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Research Team

S

Sarah LEBLANC, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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