Actively Recruiting
Hairy Cell Leukemia Study of Extracellular Vesicles to Improve Patient Care Management
Led by IRCCS Azienda Ospedaliero-Universitaria di Bologna · Updated on 2025-01-08
50
Participants Needed
1
Research Sites
156 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are investigating extracellular vesicles, tiny particles found in blood plasma that carry proteins, lipids, and nucleic acids, to better understand their role in Hairy Cell Leukemia (HCL). This study aims to find unique biological and disease-related markers by analyzing these vesicles in patients with HCL at different stages, such as newly diagnosed, in remission for over two years, or with relapsed disease needing therapy. The study focuses on characterizing extracellular vesicles from patients and comparing them to those from healthy donors. There are no specific interventions or treatments being tested; instead, blood samples will be analyzed to identify differences in the vesicles that may relate to the disease and its progression. Participants will provide samples for detailed examination of extracellular vesicles over a period of up to two years. Researchers will monitor changes and features of these vesicles to develop potential biomarkers that could help improve patient care and management in the future. The study includes adults aged 18 or older, both patients with HCL and healthy volunteers, with no exclusion criteria applied.
CONDITIONS
Official Title
Hairy Cell Leukemia: Harnessing the Full Power of Extracellular Vesicles to Improve Patient Care Management
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of Hairy Cell Leukemia according to WHO2022 criteria
- Age 18 years or older
- Signed informed consent
- For healthy donors: age 18 years or older
- For healthy donors: generally in good health and free from any disease or serious illness
- For healthy donors: signed informed consent
You will not qualify if you...
- None
AI-Screening
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Trial Site Locations
Total: 1 location
1
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Bologna, Italy, 40138
Actively Recruiting
Research Team
L
Lucia Catani, PhD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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