Actively Recruiting

Age: 18Years +
All Genders
Healthy Volunteers
ID05404750

Impact of Harm Reduction Care in HIV Clinical Settings on Stigma and Health Outcomes

Led by University of Pittsburgh ยท Updated on 2026-04-24

768

Participants Needed

3

Research Sites

N/A

Total Duration

On this page

Sponsors

U

University of Pittsburgh

Lead Sponsor

A

Allegheny Health Network

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are examining how harm reduction approaches in healthcare affect people living with HIV (PLWH) who use drugs. The study explores how healthcare providers' attitudes towards PLWH who use drugs relate to their use of harm reduction strategies and how these approaches influence patients' experiences of stigma and clinical outcomes. This research aims to inform the development of interventions to improve care and reduce health disparities for PLWH who use drugs. This observational study involves healthcare providers and patients at three clinical sites. Providers working in various roles related to HIV care will be surveyed and interviewed about their attitudes and practices regarding harm reduction. Patients living with HIV who use drugs will be surveyed about their experiences with stigma, relationships with providers, and harm reduction care. Findings will guide the creation and testing of a new intervention to enhance harm reduction practices in HIV care. Participants will complete surveys and interviews to assess providers' attitudes and patients' perceptions of harm reduction and stigma. Clinical outcomes such as HIV viral load, retention in care, medication adherence, and hepatitis C viral load will be reviewed retrospectively over the past five years. The study includes both qualitative and quantitative data collection to understand the impact of harm reduction care on health outcomes and patient-provider relationships.

CONDITIONS

Brief Title

Harm Reduction in HIV Primary Care for PLWH Who Use Drugs

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Providers must have worked at one of the study sites or partner substance use treatment sites for at least one year
  • Providers must provide service or care to PLWH or people who use drugs at high risk for HIV
  • Providers must work in roles such as front desk/patient engagement, social worker, nurse, medical assistant, advanced practice provider, or physician
  • Providers must be able to verbally consent, read, and speak English
  • Patients must be living with HIV
  • Patients must be 18 years or older
  • Patients must be able to verbally consent, read, and speak English
  • Patients must have received HIV medical care at one of the study sites for at least one year
  • Patients must have lifetime or recent (past 3 months) use of illicit substances (excluding marijuana) or prescription drugs for non-medical reasons according to NIDA-Modified ASSIST 2.0
Not Eligible

You will not qualify if you...

History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person or remote) to confirm eligibility and obtain consent

Monitoring

Duration - Up to several years, retrospective data from past 5 years will be reviewed

Participants who receive routine HIV care and have a history of substance use are observed to understand the impact of harm reduction care on stigma experiences and clinical outcomes.

Participants continue their regular HIV care visits; study surveys and interviews occur during routine visits or remotely

Trial Site Locations

Total: 3 locations

1

University of Alabama at Birmingham

Birmingham, Alabama, United States, 35222

Actively Recruiting

2

Allegheny Health Network Research Institute

Pittsburgh, Pennsylvania, United States, 15212

Actively Recruiting

3

University of Pittsburgh Medical Center

Pittsburgh, Pennsylvania, United States, 15213

Actively Recruiting

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Research Team

M

Mary Hawk, DrPH

S

Stephanie Creasy, MPH

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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Published Research Related To This Trial

"Let me hear what you're needing": exploring how HIV providers conceptualize patient-provider interactions with people with HIV who use drugs using a harm reduction framework.

Stephanie L Creasy, James E Egan, Sarah Krier...

https://pubmed.ncbi.nlm.nih.gov/40017794

Impact of harm reduction care in HIV clinical settings on stigma and health outcomes for people with HIV who use drugs: study protocol for a mixed-methods, multisite, observational study.

Emma Sophia Kay, Stephanie Creasy, D Scott Batey...

https://pubmed.ncbi.nlm.nih.gov/36113946