Actively Recruiting
Harm Reduction for Smokers With Mental Illness
Led by Dartmouth-Hitchcock Medical Center · Updated on 2026-01-15
250
Participants Needed
2
Research Sites
182 weeks
Total Duration
On this page
Sponsors
D
Dartmouth-Hitchcock Medical Center
Lead Sponsor
D
Dartmouth College
Collaborating Sponsor
AI-Summary
What this Trial Is About
To compare the efficacy of e-cigarette (e-cig) provision with or without behavioral support (SWITCH IT) delivered via telehealth to reduce harm among smokers with MI who cannot quit smoking and are not ready to pursue cessation treatment, and to examine self-regulation (using e-cigs instead of cigarettes to cope with stress/distress and self-efficacy) as a potential mechanism for behavior change from SWITCH IT
CONDITIONS
Official Title
Harm Reduction for Smokers With Mental Illness
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosed with schizophrenia, bipolar disorder, major depressive disorder, posttraumatic disorder, or another anxiety disorder
- 21 years or older
- English-speaking
- Daily smoker of at least 10 cigarettes per day
- At least one quit attempt in the past 5 years using evidence-based medication or behavioral support
- Not currently interested in quitting smoking
You will not qualify if you...
- Currently living in a nursing home
- Current diagnosis of asthma
- Cognitive impairment (score less than 26 on Telephone Interview for Cognitive Status)
- Using e-cigarettes more than once a week currently
- Psychiatric instability (hospitalized in the past month)
- Current moderate to severe substance use disorder
- Pregnant or planning to become pregnant
- Use of smoked products other than cigarettes
- Unstable medical illness making e-cigarette use unsafe (e.g., recent heart attack, cancer)
- Participation in SWITCH IT pilot study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Seven Counties Services
Louisville, Kentucky, United States, 40203
Actively Recruiting
2
The Providence Center
Providence, Rhode Island, United States, 02903
Actively Recruiting
Research Team
M
Meghan M. Santos, MSW
CONTACT
G
Gail Williams, MS, MFT
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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