Actively Recruiting

Phase Not Applicable
Age: 0 - 2Years
All Genders
NCT06219863

Harness-based Mobility Intervention for Infants With Down Syndrome

Led by Boston University Charles River Campus · Updated on 2025-05-14

6

Participants Needed

1

Research Sites

60 weeks

Total Duration

On this page

Sponsors

B

Boston University Charles River Campus

Lead Sponsor

B

Boston Children's Hospital

Collaborating Sponsor

AI-Summary

What this Trial Is About

The emergence of crawling and walking is significantly delayed in infants with Down syndrome (DS), but the development of independent mobility provides infants with new opportunities for exploring the environment and interacting with objects and people that are important foundations for early learning. Increasing infant mobility early in development with body weight supported harness systems may support infant exploration, communication, and social interaction. This project will set the stage for the first clinical trial of a mobility-related intervention specifically tailored for infants with DS by testing the feasibility of harness systems with infants and families and identifying measures that will serve as primary outcome variables. Upon completion of this pilot project, necessary preliminary data and experience required for an in-home, high-impact clinical trial for infants with DS will have been obtained.

CONDITIONS

Official Title

Harness-based Mobility Intervention for Infants With Down Syndrome

Who Can Participate

Age: 0 - 2Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Confirmed diagnosis of Trisomy 21
  • Younger than 24 months
  • English is the primary language of the home
  • Able to sit without support
  • Not yet taking any independent steps
Not Eligible

You will not qualify if you...

  • Mosaic or Translocation Down syndrome
  • Severe, uncontrolled medical problems including heart disease with cardiovascular instability or uncontrolled epilepsy
  • Severe uncorrected hearing or vision impairments

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Boston University

Boston, Massachusetts, United States, 02215

Actively Recruiting

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Research Team

A

Anna Donato

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

OTHER

Number of Arms

1

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