Actively Recruiting

Age: 18Years - 65Years
All Genders
NCT05977283

HBsAg Declined Patients Follow-up Study

Led by Nanfang Hospital, Southern Medical University · Updated on 2024-02-20

100

Participants Needed

1

Research Sites

250 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this observational study is to prospectively follow chronic hepatitis B patients who had HBsAg decline in the past 12 months prior to screening. The main question it aims to answer are: \- Describe treatment pattern and its impact on HBsAg loss in hepatitis B patients who had HBsAg decline in past 12 months due to any reason (with or without new molecular entities therapy). Participants will be followed up for 36 months after enrollment and may be extended upon expiration according to study objectives.

CONDITIONS

Official Title

HBsAg Declined Patients Follow-up Study

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Participants must have experienced a decline in HBsAg levels of at least 0.5 log10 IU/mL in the past 12 months due to any reason, with or without new molecular therapy.
  • Among enrolled participants, 70% must have a decline of at least 1 log10 IU/mL or actual values of 3 log10 IU/mL or less.
  • Able and willing to provide written informed consent and comply with the study protocol according to International Council for Harmonization (ICH) and local regulations.
Not Eligible

You will not qualify if you...

  • Any condition that, in the investigator's opinion, makes participation in the study unsafe or inappropriate.
  • Currently enrolled in an interventional clinical study exploring hepatitis B virus treatment.

AI-Screening

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Trial Site Locations

Total: 1 location

1

Nanfang Hospital, Southern Medical University

Guangzhou, Guangdong, China, 510000

Actively Recruiting

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Research Team

X

Xieer Liang, M.D.

CONTACT

Z

Zhihong Liu, M.D.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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