Actively Recruiting
HDV-Europe: Prevalence and Outcome of HDV in HIV/HBV Coinfection
Led by University Hospital, Bonn · Updated on 2024-05-24
8000
Participants Needed
1
Research Sites
60 weeks
Total Duration
On this page
Sponsors
U
University Hospital, Bonn
Lead Sponsor
S
Swiss HIV Cohort Study
Collaborating Sponsor
AI-Summary
What this Trial Is About
The aim of this project is to set up a cross-sectional cohort study (France, Germany, The Netherlands, Poland, Spain, Switzerland, Italy, United Kingdom and Portugal) to assess the implementation of EACS guidelines for HDV-testing among PLWH with positive HbsAg and thereby evaluate the prevalence of HDV infection among HIV/HBV-coinfected in 2023, as well as corresponding risk factors. In addition to the testing itself, this study will also set up a cohort and databasee for future HDV studies among PLWH, including clinical, virological und laboratory parameters. 1. Analyze the rate of HDV-testing and evaluate the prevalence of HDV-infection by testing. 1. Evaluation of former screening of HDV by assessing existing data at study sites. 2. Determination of the HDV prevalence in European PLWH and HBV coinfection. 2. Setting up a database of all PLWH with HBV/HDV coinfection 1. Analysis of transmission risk factors for HDV coinfection 2. Asses the rate of HDV positive patients with ongoing HDV replication. 3. Define the liver disease state by APRI score, fibroscan, ultrasound and routine laboratory test results.
CONDITIONS
Official Title
HDV-Europe: Prevalence and Outcome of HDV in HIV/HBV Coinfection
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Documented HIV infection confirmed by HIV-ELISA
- Chronic Hepatitis B infection confirmed by two positive HBsAg tests taken more than 6 months apart
You will not qualify if you...
- People living with HIV who have cleared Hepatitis B infection (anti-HBc or anti-HBc and anti-HBs antibody positive)
- Individuals younger than 18 years old
- Patients with social or living conditions that may prevent proper study participation or understanding
- In France, patients without adequate social security coverage
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
University Hospital Bonn
Bonn, North Rhine-Westphalia, Germany, 53127
Actively Recruiting
Research Team
J
Jürgen Rockstroh
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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