Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
Healthy Volunteers
NCT06417216

Head-Cancelled Virtual Reality for Ocular Cranial Nerve Palsies

Led by Kevin Houston · Updated on 2026-04-06

40

Participants Needed

2

Research Sites

194 weeks

Total Duration

On this page

Sponsors

K

Kevin Houston

Lead Sponsor

A

American Academy of Optometry

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study is investigating whether eye exercises for abducens palsy and internuclear ophthalmoplegia increase ocular range of motion in the paretic direction when performed in virtual reality under head-cancelled compared to head-active conditions.

CONDITIONS

Official Title

Head-Cancelled Virtual Reality for Ocular Cranial Nerve Palsies

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Presence of ocular cranial nerve palsy in one eye with 50% range-of-motion limitation or worse
  • Able to provide informed consent and fluently read and understand spoken English
  • Absence of ocular cranial nerve palsy or other neurological or neuro-ophthalmic diseases (for normal control group)
  • No strabismus (for normal control group)
  • Normal or near-normal vision with glasses or contact lenses (for normal control group)
Not Eligible

You will not qualify if you...

  • Presence of bilateral ocular cranial nerve palsy
  • Range of motion better than 50%
  • Visual acuity worse than 20/100 in either eye
  • Greater than 4-line difference in visual acuity between the eyes
  • Structural anomalies or sensory sensitivities preventing wearing or tolerating a VR headset
  • Known inability to tolerate visual testing continuously for at least 20 minutes
  • Unable to participate if inclusion criteria are not met

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Brooks Rehabilitation Hospital

Jacksonville, Florida, United States, 32216

Actively Recruiting

2

Vision Source of Worcester

Worcester, Massachusetts, United States, 01610

Actively Recruiting

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Research Team

K

Kevin Houston, OD

CONTACT

S

Shelli Levasseur, BS

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

TREATMENT

Number of Arms

2

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