Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT02678884

Head and Neck Squamous Cell Carcinoma (HNSCC)PET-CT Pilot Study

Led by University Health Network, Toronto · Updated on 2024-03-13

20

Participants Needed

1

Research Sites

735 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this study is to see how useful the information provided from Positron Emission Tomography (PET) scans can be in the actual planning and delivery of radiation treatment to patients who have head and neck cancers. Patients participating in this study, will have (in addition to their routine tests) a PET scan before and during their radiation treatment. Following the intervention, patients will be followed as per standard practice.

CONDITIONS

Official Title

Head and Neck Squamous Cell Carcinoma (HNSCC)PET-CT Pilot Study

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Non-nasopharynx head and neck mucosal squamous cell carcinoma
  • Radiologically evident gross disease
  • Receiving radiotherapy alone with curative intent
  • Age 18 years or older
  • FDG avid tumor with minimum SUV of 2.5 on the first PET-CT scan to be eligible for the second PET-CT scan
Not Eligible

You will not qualify if you...

  • Nasopharynx cancer
  • Head and neck squamous cell carcinoma of the skin
  • Presence of distant metastases known or found on baseline CT of the thorax
  • Prior malignancy within the last 5 years (excluding non-H&N SCC and basal cell carcinoma of the skin)
  • Prior chemotherapy within the last 5 years or concurrent chemotherapy/EGFR inhibitor treatment
  • Prior head and neck radiotherapy
  • Inability to lie supine for the duration of the study
  • Pregnancy
  • Inability to provide informed consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University Health Network, Princess Margaret Cancer Center

Toronto, Ontario, Canada, M5G 2M9

Actively Recruiting

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Research Team

J

John J Kim, MD

CONTACT

S

Stephen Breen, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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Head and Neck Squamous Cell Carcinoma (HNSCC)PET-CT Pilot Study | DecenTrialz