Actively Recruiting
Headache Registration and Follow-up Initiated by Tongji Hospital, HUST
Led by Tongji Hospital · Updated on 2025-12-08
50000
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Headache is a common and complex condition affecting many people globally, often leading to a reduced quality of life. This study aims to build a clinical cohort and develop a precise diagnosis and treatment system for headaches using advanced biotechnologies, multi-omics detection, and big data analysis. The research is part of a major project in Hubei Province focusing on genetic big data and seeks to improve headache diagnosis and treatment approaches. The study is a multi-center, prospective observational research involving 50,000 headache patients from various centers in China. It collects detailed clinical, epidemiological, imaging, and questionnaire data, along with biological samples from 1,500 patients at Tongji Hospital. Participants will be followed up monthly for the first three months with face-to-face interviews, then annually via telephone for up to 10 years. The study integrates clinical data with biological and multi-omics information to support precision medicine development. Participants will provide detailed headache histories and undergo various assessments including blood sample collection, imaging, and questionnaires. The research tracks medication use, treatment effects, and adverse reactions over time. The main outcome is the development of an integrated precision diagnosis and treatment system for headaches, with secondary outcomes including brain network and biomarker studies, treatment efficacy, and identification of new therapeutic targets. This long-term study offers extensive data collection and follow-up to support improved headache care.
CONDITIONS
Brief Title
Headache Registration and Followup Initiated by Tongji Hospital, HUST
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosed with headache according to the International Classification of Headache Disorders 3rd edition (ICHD-3, 2018)
- Age between 6 and 70 years
- Voluntary participation with informed consent
- Able to comply with follow-up visits and complete questionnaires
You will not qualify if you...
- Complex headache causes involving three or more distinct factors
- Severe systemic diseases or life expectancy less than 10 years
- Significant cognitive or psychiatric problems preventing completion of questionnaires and clinical assessments
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 10 years
Participants who undergo routine care are observed with data collection including epidemiological information, clinical data, neuroimaging, questionnaires, and blood sample collection for precision medicine research.
Face-to-face interviews during the first three months and annual telephone follow-ups thereafter
Trial Site Locations
Total: 1 location
1
Tongji hospital, Tongji Medical College, Huazhong University of Science and Technology
Wuhan, Hubei, China, 430030
Actively Recruiting
Research Team
W
Wensheng Qu Professor, DM PhD
H
Han Zhang Dr, MD PhD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here