Actively Recruiting

Phase Not Applicable
Age: 18Years - 25Years
All Genders
ID06386198

HEalth Advocate for Liver Transplantation: Improving Transition of Care for Adolescent Liver Transplant Recipients

Led by University of California, San Francisco · Updated on 2025-05-13

20

Participants Needed

2

Research Sites

N/A

Total Duration

On this page

Sponsors

U

University of California, San Francisco

Lead Sponsor

A

American Society of Transplantation

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are evaluating a Health Advocate intervention to support adolescents and young adults who have undergone liver transplantation as they transition their care from pediatric to adult transplant teams. This pilot study aims to assess how feasible and acceptable it is to integrate a Health Advocate into the transplant care team. The Health Advocate helps address unmet social needs, improves communication between patients and providers, and connects patients to community resources to enhance self-management and overall care coordination. The study features a single intervention group where participants receive support from a Health Advocate. This intervention includes assistance with social challenges such as food insecurity, improving communication with healthcare providers, and coordinating care across different services. The intervention is tailored to young liver transplant recipients and their families and is delivered over a period allowing baseline and 180-day follow-up assessments. Participants will be involved for at least 180 days during which researchers will measure changes in patient experience and medication adherence using the Medication Level Variability Index (MLVI). The study also evaluates the quality of interactions between the Health Advocate, healthcare teams, and community resources. Patient and provider satisfaction with the intervention will be assessed qualitatively. Participants engage through virtual visits enabled by a working phone or smart device capable of video or audio communication.

CONDITIONS

Brief Title

HEalth Advocate for Liver Transplantation: Improving Transition of Care for Adolescent Liver Transplant Recipients

Who Can Participate

Age: 18Years - 25Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patient has received a liver transplant more than 1 year ago
  • Patient has been screened and considered likely to benefit from the Health Advocate program by the primary transplant practitioner
  • Patient has an unmet social risk (such as food insecurity) or a Medication Level Variability Index (MLVI) of 2.0 or higher
  • Patient will transfer to an adult transplant team within 6 months
  • Patient can read and write English or Spanish
  • Patient is between 18 and 25 years old and can provide informed consent
  • Patient has a working phone and smart device capable of video or audio virtual visits via Zoom
Not Eligible

You will not qualify if you...

  • Patient has significant cognitive impairment
  • Patient does not meet age criteria
  • Patient is a ward of the state
  • Patient does not speak English or Spanish
  • Patient is not a US resident

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person or virtual)

Outpatient Treatment

Duration - 180 days

Participants receive support from a Health Advocate to address unmet social needs, improve communication with healthcare providers, and enhance care coordination.

Regular virtual visits via Zoom during the intervention period

Follow-up

Duration - Up to 180 days after baseline

Participants are assessed for changes in patient experience, medication adherence, and satisfaction with the Health Advocate intervention.

Assessments at baseline and at 180 days

Trial Site Locations

Total: 2 locations

1

University of California San Francisco

San Francisco, California, United States, 94158

Actively Recruiting

2

Children's Healthcare of Atlanta

Atlanta, Georgia, United States, 30345

Not Yet Recruiting

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Research Team

S

Sharad Wadhwani, MD, MPH

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

1

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