Actively Recruiting
Health Effects of the Standardized Research E-Cigarette in Smokers With HIV Smokers With HIV
Led by Brown University · Updated on 2024-06-18
72
Participants Needed
1
Research Sites
147 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Cigarette smoking is more prevalent (50-70%) in persons living with HIV in the U.S. when compared with the general population and is linked to increased rates of heart disease, lung diseases and infections, and lung cancers. Because of their high levels of nicotine dependence, low quit rates, and familiarity with harm reduction, HIV-positive smokers may view the use of alternative nicotine delivery products, such as electronic cigarettes (ECs), as an attractive option for reducing and eventually stopping combustible cigarette use. However, little is known about the health effects of electronic cigarette use in HIV-positive smokers. Some studies have shown that electronic cigarette use was associated with increased confidence to quit smoking in the general population. The primary objectives of this project are to examine whether HIV-positive smokers, who are unwilling or unable to quit smoking, will substitute an electronic cigarette for regular cigarettes, and to examine whether there are any changes in heart and lung health in HIV-positive smokers who switch from regular cigarettes to electronic cigarettes.
CONDITIONS
Official Title
Health Effects of the Standardized Research E-Cigarette in Smokers With HIV Smokers With HIV
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosed with and engaged in care for HIV (at least one HIV clinic appointment in the past six months)
- At least 18 years of age
- Smoke at least 5 cigarettes per day for longer than one year
- Exhaled carbon monoxide level greater than 5 at baseline
You will not qualify if you...
- Planning to quit smoking within the next 30 days
- Currently using medication for smoking cessation
- Currently using electronic cigarettes more than 2 days per week
- Hospitalized due to unstable medical or psychiatric condition
- Medical reasons that make nicotine unsafe (unstable angina, uncontrolled high blood pressure, recent heart event or hospitalization)
- Experiencing psychotic symptoms
- Having substance use disorder other than nicotine dependence
- Suicidal thoughts in the past month or suicide attempt in the past year
- Pregnant or breastfeeding
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Brown University School of Public Health
Providence, Rhode Island, United States, 02912
Actively Recruiting
Research Team
P
PATRICIA A CIOE, PhD
CONTACT
J
Jasmine DiLorenzo, BA
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
2
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