Actively Recruiting
Health Outcomes of Parents With Cystic Fibrosis-Aim 2
Led by University of Pittsburgh · Updated on 2025-11-10
146
Participants Needed
18
Research Sites
348 weeks
Total Duration
On this page
Sponsors
U
University of Pittsburgh
Lead Sponsor
C
Cystic Fibrosis Foundation
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this observational prospective study is to determine the health impact of parenthood on United States (US) people with CF in the era of CF transmembrane regulator protein (CFTR) modulators. The investigators will collect physical and mental health data to comprehensively evaluate the impact of parenthood in CF with widespread highly effective CFTR modulator use. The main hypotheses this study aims to examine are: H1: Parents with CF and moderate-to-severe depression have more rapid change in ppFEV1 (percent predicted forced expiratory volume in one second) versus those with mild or no depression. H2: Parents with CF who have more parental responsibility and/or stress have more rapid ppFEV1 (percent predicted forced expiratory volume in one second) change than those with less responsibility/stress H3: Parents using CFTR modulators have decreased ppFEV1 (percent predicted forced expiratory volume in one second) change versus those not using CFTR modulators Participants will complete quarterly surveys during the first year of parenthood and biannual surveys, thereafter, using the computer-based survey system on an iPad protected for infection control or via personal device or computer via emailed survey link.
CONDITIONS
Official Title
Health Outcomes of Parents With Cystic Fibrosis-Aim 2
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosed with cystic fibrosis via sweat test or genotype analysis
- Became a first-time parent (including foster parent, step parent, adoptive parent, or legal guardian) to a child under 5 years of age within the last 180 days
You will not qualify if you...
- Undergone a lung transplant
- Does not speak/read English or Spanish
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 18 locations
1
University of Alabama-Birmingham
Birmingham, Alabama, United States, 35294
Actively Recruiting
2
National Jewish Health
Denver, Colorado, United States, 80206
Actively Recruiting
3
Northwestern University
Evanston, Illinois, United States, 60208
Not Yet Recruiting
4
Indiana University
Indianapolis, Indiana, United States, 46202
Actively Recruiting
5
University of Kansas Medical Center
Kansas City, Kansas, United States, 66160
Actively Recruiting
6
Johns Hopkins University
Baltimore, Maryland, United States, 21218
Actively Recruiting
7
Massachusetts General Hospital
Boston, Massachusetts, United States, 02114
Actively Recruiting
8
Boston Children's Hospital/Brigham and Women's Hospital
Boston, Massachusetts, United States, 02115
Actively Recruiting
9
University of Michigan
Ann Arbor, Michigan, United States, 48109
Actively Recruiting
10
University of Minnesota
Minneapolis, Minnesota, United States, 55455
Actively Recruiting
11
Washington University School of Medicine
St Louis, Missouri, United States, 63110
Actively Recruiting
12
University of North Carolina
Chapel Hill, North Carolina, United States, 27599
Actively Recruiting
13
Oregon Health and Science University
Portland, Oregon, United States, 97239
Actively Recruiting
14
University of Pennsylvania
Philadelphia, Pennsylvania, United States, 19104
Actively Recruiting
15
University of Pittsburgh
Pittsburgh, Pennsylvania, United States, 15213
Actively Recruiting
16
Medical University of South Carolina
Charleston, South Carolina, United States, 29425
Actively Recruiting
17
University of Texas-Southwestern
Dallas, Texas, United States, 75390
Actively Recruiting
18
University of Washington
Seattle, Washington, United States, 98195
Actively Recruiting
Research Team
O
Olivia M Stransky, MPH
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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