Actively Recruiting

Phase Not Applicable
Age: 45Years - 75Years
All Genders
Healthy Volunteers
NCT07227259

Health Properties of Pecan Nut Consumption

Led by University of California, Davis · Updated on 2026-02-24

40

Participants Needed

1

Research Sites

106 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The main goal of this clinical study is to see if consuming pecan nuts will result in improvements in overall body metabolism such as in blood lipids, markers of inflammation, blood pressure, cognitive performance and changes in bacteria living in the gut in adults 45 to 75 years of age. Participants will take part in two 3-month intervention periods, separated by 4-6 weeks, in random order ( a total of approximately 7 months). During one intervention period, they will include pecan nuts in their diet each day, while during the other intervention period they will avoid pecans in their diet. There will be an initial screening visit to evaluate eligibility and four study visits to the clinic. Participants will be asked to complete some questionnaires about their diet, physical and cognitive health, and provide blood and stool samples, and have their blood pressure measured.

CONDITIONS

Official Title

Health Properties of Pecan Nut Consumption

Who Can Participate

Age: 45Years - 75Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 45 to 75 years
  • Body mass index (BMI) between 20 and 35 kg/m2
  • Ability to understand the intervention instructions
  • Willingness to follow the dietary intervention
  • Willingness to provide biological samples including blood and stool
Not Eligible

You will not qualify if you...

  • Allergy to pecan nuts or other nuts
  • Cognitive impairment due to any type of dementia or inability to understand or follow instructions
  • Use of menopausal hormone replacement therapy
  • Use of antibiotics or probiotics within 2 months before enrollment
  • Uncontrolled diabetes with HbA1C greater than 9.5
  • Being vegetarian or vegan
  • Having serious medical conditions such as stage 3 or greater chronic kidney disease, heart failure, active cancer treatment, or inflammatory bowel disease
  • Use of supplements that may affect vascular response or gut microbiome
  • Use of statin drugs for lowering cholesterol

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Ragle Human Nutrition Center, UC Davis campus

Davis, California, United States, 95616

Actively Recruiting

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Research Team

F

Francene Steinberg, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

PREVENTION

Number of Arms

2

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