Study of Visual and Brain Function in Babies with Hypoxic-Ischemic Encephalopathy Using Eye Tests to Predict Development from Birth to 3 Years

What this Trial Is About

This research aims to better understand how eye injuries relate to a babys future development, focusing on babies with hypoxic-ischemic encephalopathy HIE. The study explores whether eye function tests and brain test results can improve diagnosis and treatment for these babies. It is a longitudinal observational study that tracks visual and brain outcomes in children with HIE compared to healthy babies. Participants will undergo eye exams including Visual Evoked Potential VEP and Electroretinogram ERG tests. These involve placing electrodes on the head or skin around the eyes while exposing the eyes to light flickers. Each eye is tested separately, and some babies without HIE are also tested as a comparison group. Data will be collected at birth and multiple points up to 36 months of age. During the study, babies will have up to two eye exam sessions and their neurodevelopment and neuroimaging outcomes will be monitored through 30 months of life. Researchers will analyze eye function, brain imaging, and developmental tests to find correlations. The goal is to develop new, noninvasive tools that help improve long-term outcomes for babies affected by HIE.

Healthy Little Eyes