Actively Recruiting
Healthy Volunteers Study
Led by Abramson Cancer Center at Penn Medicine · Updated on 2026-02-05
50
Participants Needed
1
Research Sites
109 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to examine the role of the bacterial environments and metabolites in the early detection and prediction of ovarian cancer development. Vaginal swabs and stool samples will be collected from healthy volunteers, or those without a known ovarian cancer diagnosis or genetic ovarian cancer risk. These samples will be compared to samples from participants with increased cancer risk and ovarian cancer diagnoses.
CONDITIONS
Official Title
Healthy Volunteers Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Female with ovaries
- Age between 30 and 50 years
- No known ovarian cancer diagnosis
- No known genetic ovarian cancer risk mutations
- Able to provide vaginal swab and stool samples
You will not qualify if you...
- Presence of genetic mutations increasing ovarian cancer risk: BRCA1/2, BRIP1, PALB2, Lynch Syndrome (MLH1, MSH2/EPCAM, MSH6), or ATM
- Unknown or no genetic testing results
- Prior cancer diagnosis
- Prior cancer treatment
- Use of hormone replacement therapy (HRT)
- Antibiotic use within 1 month before sample collection
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Abramson Cancer Center of the University of Pennsylvania
Philadelphia, Pennsylvania, United States, 19104
Actively Recruiting
Research Team
C
Catherine Wolfe, BA
CONTACT
J
Jamie Brower, MS
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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