Predicting Emergence Agitation After Septorhinoplasty by Studying Heart Rate Variability and Anxiety in Adults Undergoing General Anesthesia

What this Trial Is About

This research aims to explore whether preoperative heart rate variability HRV and anxiety levels are linked to and can help predict emergence agitation in adults undergoing elective septorhinoplasty with general anesthesia. Emergence agitation is a notable condition during early recovery from anesthesia, possibly influenced by autonomic nervous system activity and psychological factors. The study is being conducted at a single center and plans to enroll about 100 adult patients. Participants will undergo routine general anesthesia for their septorhinoplasty. Before surgery, their anxiety will be measured using a visual analog scale VAS and the State-Trait Anxiety Inventory STAI-1. Resting HRV will be recorded preoperatively using a chest-strap heart rate monitor to calculate various HRV parameters such as SDNN, RMSSD, and LFHF. After surgery, emergence agitation will be assessed in the post-anesthesia care unit PACU using the Richmond Agitation-Sedation Scale RASS during the first 30 minutes of recovery. Additional observations will include monitoring for postoperative nausea and vomiting PONV within 24 hours and laryngospasm from extubation until discharge from the PACU. Throughout the study, participants will complete anxiety questionnaires before surgery and wear the heart rate monitor to record HRV. Postoperative agitation will be regularly assessed using the RASS scale in the PACU. Researchers will track other recovery events like nausea, vomiting, and laryngospasm. The primary outcome is the incidence of emergence agitation within 30 minutes after arrival to the PACU. The study will provide insights on whether HRV and anxiety can predict early recovery agitation, with outcomes monitored until discharge from the PACU and 24 hours postoperatively.

Heart Rate Variability and Anxiety as Predictors of Emergence Agitation After Septorhinoplasty