Actively Recruiting

Phase Not Applicable
Age: 13Years - 18Years
All Genders
NCT06537258

Heart Rate Variability and Inflammatory Bowel Disease

Led by Emory University · Updated on 2026-04-01

128

Participants Needed

3

Research Sites

190 weeks

Total Duration

On this page

Sponsors

E

Emory University

Lead Sponsor

N

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goals of this study are to test the effectiveness of a virtually delivered, group-based coping skills treatment program incorporating heart rate variability biofeedback to target autonomic dysfunction in youth diagnosed with inflammatory bowel disease (IBD). The investigators will enroll participants with IBD in a biofeedback enhanced cognitive behaviorally based coping skills treatment. Participants will be randomized to biofeedback enhanced treatment or wait-list control.

CONDITIONS

Official Title

Heart Rate Variability and Inflammatory Bowel Disease

Who Can Participate

Age: 13Years - 18Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosed with biopsy-confirmed inflammatory bowel disease for at least 4 months
  • Ages 13 through 18 years inclusive
  • Able to speak English
  • Enrolling with at least one parent or guardian who will complete surveys
  • Positive depression or anxiety screen using the PHQ-4
  • Access to home internet for virtual intervention participation
  • Youth and parent agree to study conditions including randomization, intervention, and follow-ups
  • Youth is medically cleared to engage in normal daily activities like school and extracurriculars
Not Eligible

You will not qualify if you...

  • Previous diagnosis of developmental disabilities requiring full-time special education or impairing treatment response
  • Diagnosis of any other chronic disease such as diabetes or epilepsy
  • Diagnosis of abnormal thyroid function
  • Currently treated with drugs affecting autonomic cardiovascular function, including beta-blockers, central sympatholytic agents, or antidepressants

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 3 locations

1

Atlanta Metropolitan Area

Atlanta, Georgia, United States, 30303

Actively Recruiting

2

Children's Healthcare of Atlanta

Atlanta, Georgia, United States, 30322

Actively Recruiting

3

Center for Advanced Pediatrics

Atlanta, Georgia, United States, 30329

Actively Recruiting

Loading map...

Research Team

B

Bonney Reed, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here