Actively Recruiting
Heartburn, Gastroesophageal Reflux Disease
Led by Incheon St.Mary's Hospital · Updated on 2025-12-23
160
Participants Needed
10
Research Sites
64 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Gastroesophageal reflux disease (GERD) is a condition caused by the reflux of stomach contents into the esophagus, presenting with typical symptoms such as heartburn and acid regurgitation. GERD is a chronic condition that affects quality of life, and patients with this condition are known to have a lower quality of life compared to healthy individuals. In particular, nocturnal heartburn can lead to sleep deprivation and affect daily life, as well as overall quality of life. This study aims to evaluate the efficacy of alleviating nocturnal heartburn symptoms in patients with erosive reflux disease (ERD).
CONDITIONS
Official Title
Heartburn, Gastroesophageal Reflux Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Korean adults aged 19 years or older
- Diagnosed with erosive gastroesophageal reflux disease by upper gastrointestinal endoscopy
- Experienced nighttime heartburn for more than 3 months at screening
- Voluntarily agree to participate and provide written informed consent
You will not qualify if you...
- Unable to undergo upper gastrointestinal endoscopy
- History of drug or alcohol abuse within the past year
- Received other investigational products within one month before screening
- Any clinically significant condition deemed inappropriate for study participation by the investigator
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 10 locations
1
Korea University Ansan Hospital
Ansan, South Korea
Actively Recruiting
2
Pusan National University Hospital
Busan, South Korea
Actively Recruiting
3
Kyungpook National University Chilgok Hospital
Chilgok, South Korea
Actively Recruiting
4
Hallym University Chuncheon Sacred Heart Hospital
Chuncheon, South Korea
Actively Recruiting
5
Chonnam National University Hospital
Gwangju, South Korea
Actively Recruiting
6
Catholic University of Korea, Incheon ST. Mary's Hospital
Incheon, South Korea
Actively Recruiting
7
Gangnam Severance Hospital
Seoul, South Korea
Actively Recruiting
8
Kyung Hee University Hospital
Seoul, South Korea
Actively Recruiting
9
Soonchunhyang University Hospital
Seoul, South Korea
Actively Recruiting
10
Pusan National University Yangsan Hospital
Yangsan, South Korea
Actively Recruiting
Research Team
B
Byung-Wook Kim
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
2
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