Actively Recruiting
Heat Therapy, Functional Capacity, and Vascular Health in Older Adults
Led by University of North Texas Health Science Center · Updated on 2023-12-13
72
Participants Needed
1
Research Sites
195 weeks
Total Duration
On this page
Sponsors
U
University of North Texas Health Science Center
Lead Sponsor
A
American Heart Association
Collaborating Sponsor
AI-Summary
What this Trial Is About
To test the hypothesis that home-based leg heat therapy improves functional capacity, vascular function, and exercise hyperemia in older adults.
CONDITIONS
Official Title
Heat Therapy, Functional Capacity, and Vascular Health in Older Adults
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 55 and 80 years
- No tobacco or nicotine use in the past 6 months
- Systolic blood pressure less than 140 mmHg and diastolic blood pressure less than 90 mmHg
- Normal 12-lead ECG reviewed by a physician
- Normal results from a medical exam reviewed by a board-certified physician
- Body mass index (BMI) less than 40 unless athletic or muscular build
- Post-menopausal females only
You will not qualify if you...
- Not between 55 and 80 years of age
- Body mass index (BMI) greater than 40 unless athletic or muscular build
- Use of tobacco or nicotine products within the last 6 months
- Not abstaining from exercise, alcohol, certain medications, supplements, or caffeinated substances for 24 hours before experimental sessions
- Weighing less than 80 lbs
- Use of drugs known to affect vascular function unless approved
- Use of anti-hypertensive medications or beta blockers
- Daily use of bronchodilators
- Current use of anti-coagulant therapy
- Current hormone replacement therapy
- Current diagnosis of cancer
- Signs of uncontrolled cardio-metabolic abnormalities
- History of cerebrovascular problems such as stroke or epilepsy
- Known atherosclerosis
- Autonomic dysfunction
- Respiratory illnesses except exercise-induced asthma or recovered COVID-19
- History of anaphylaxis or severe needle phobia
- History of alcohol or drug abuse impacting study participation
- Latex allergy
- Allergies to study drugs
- Implanted electronic medical devices
- Tissue or skin abnormalities on legs or arms
- Current fever above 99.5�B0F (37.5�B0C)
- Use of certain medications (e.g., PDE3 inhibitors) without withholding before testing
- Diagnosis of neurological disease or cognitive dysfunction
- Recent cardiac surgery or events
- Abnormal clotting or blood clots
- History of mastectomies
- History of methemoglobinemia
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of North Texas Health Science Center
Fort Worth, Texas, United States, 76107
Actively Recruiting
Research Team
S
Steven A Romero, PhD
CONTACT
A
Amy Moore, RN
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
BASIC_SCIENCE
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here