Actively Recruiting
HEIGHT-BASED AND CONVENTIONAL SPINAL ANAESTHETIC DOSING IN GERIATRIC PATIENTS
Led by Shaheed Mohtarma Benazir Bhutto Institue of Trauma · Updated on 2026-01-23
104
Participants Needed
1
Research Sites
17 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to find out whether height-based dosing of spinal anaesthesia provides better hemodynamic stability and anesthetic outcome than conventional fixed dosing in elderly patients undergoing lower limb orthopaedic surgery.The main questions this study aims to answer are: 1. Does height-based spinal anaesthetic dosing reduce the risk of hypotension and bradycardia during surgery as compared to conventional fixed dosing? 2. Does it improve anaesthetic outcomes, such as the onset and duration of sensory and motor block?
CONDITIONS
Official Title
HEIGHT-BASED AND CONVENTIONAL SPINAL ANAESTHETIC DOSING IN GERIATRIC PATIENTS
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Individuals aged 60 to 80 years
- Any gender (male or female)
- Patients with ASA physical status I-III
- Scheduled for elective lower limb orthopedic surgeries such as fracture fixation, total knee replacement, or open reduction and internal fixation
- Planned to receive spinal anesthesia as primary anesthesia
- Provided informed written consent to participate
You will not qualify if you...
- Height less than 150 cm
- Currently taking anti-hypertensive drugs, beta blockers, or beta-agonists
- History of neurological diseases such as cerebrovascular accident or Parkinsonism
- Presence of sepsis defined by 2 or more positive SIRS criteria with positive blood or wound culture
- History of coagulation disorders like hemophilia or von Willebrand disease or use of anti-platelet drugs in the last 2 weeks
- Known allergy to study medications
- Skin infection at the spinal needle puncture site
- Undergoing emergency orthopedic surgery requiring immediate intervention
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Shaheed Mohtarma Benazir Bhutto Institue of Trauma
Karachi, Sindh, Pakistan, 74600
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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