Actively Recruiting
HELP Study - Towards High Throughput and Efficient Long-axial PET With Oral [18F]FDG
Led by British Columbia Cancer Agency · Updated on 2026-03-31
27
Participants Needed
1
Research Sites
52 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Typically, PET scans involve an IV injection of 18F-FDG that helps identify cancer. Patients are scanned 60 minutes after injecting 18F-FDG. This study aims to assess the feasibility of a different method of administration - oral ingestion (rather than IV) of 18F-FDG through delayed imaging to identify the optimal time for scanning after consuming the drug. The study will aim to recruit 15-24 individuals who will receive two PET scans - one using delayed oral 18F-FDG imaging and a second regular 18F-FDG. The analysis will focus on establishing a suitable protocol for this administration route while considering patient preference and image quality.
CONDITIONS
Official Title
HELP Study - Towards High Throughput and Efficient Long-axial PET With Oral [18F]FDG
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 19 years or older
- Participants who have received a standard of care [18F]FDG PET/CT and are willing to undergo a study specific oral [18F]FDG PET/CT within 2 weeks
You will not qualify if you...
- Pregnant or breastfeeding
- Medically unstable (e.g., acute illness, unstable vital signs)
- Urinary incontinence or use of catheter
- Immobile, frail or vulnerable patients who cannot leave the department and would require an uptake room
- Patients with fasting blood sugar greater than 11.0 mmol/l at the SOC PET
- Unable to swallow
- Patients with nasogastric tubes, percutaneous gastrostomy, or other non-anatomical nutrition routes
- Unable to lie flat for 1 hour (first 5 participants only)
- Claustrophobia requiring medication
- Undergoing active treatment or assessment of upper digestive tract tumors (stomach/esophagus)
- Unable to provide written consent
- Patients receiving biguanide anti-hyperglycemic agents (e.g. Metformin)
- Insulin dependent diabetics
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
BC Cancer Vancouver
Vancouver, British Columbia, Canada, V5Z 4E6
Actively Recruiting
Research Team
P
Pavithraa Administrative Research Manager
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SEQUENTIAL
Primary Purpose
OTHER
Number of Arms
1
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