Actively Recruiting
Hematopoietic Stem Cell-containing Autologous Blood Transfusion for Bone Marrow Protection in Patients With Cervical Cancer
Led by Chongqing University Cancer Hospital · Updated on 2023-05-01
40
Participants Needed
1
Research Sites
259 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The aim of this project is to promote the reconstruction of haematopoietic function after chemoradiotherapy for cervical cancer with the innovative use of autologous haematopoietic containing stem cell blood transfusion support.To explore the effect of stored hemopoietic stem cell support therapy on bone marrow protection after concurrent chemoradiotherapy, in order to promote its clinical application.
CONDITIONS
Official Title
Hematopoietic Stem Cell-containing Autologous Blood Transfusion for Bone Marrow Protection in Patients With Cervical Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 60 years
- Have indications for radiotherapy and chemotherapy for cervical cancer
- Pathological diagnosis of squamous, adenocarcinoma, or adenosquamous carcinoma
- Eastern Cooperative Oncology Group (ECOG) performance status score of 1 or less
- Expected survival time of more than 3 months
- Pre-menopausal women or post-menopausal for at least 12 months with negative serum pregnancy test
- Agree to use effective contraception during the study and for 6 months after treatment
- Voluntarily agree to participate, sign informed consent, and can complete study procedures and follow-up
You will not qualify if you...
- Diagnosis of bone marrow disease
- Central nervous system, soft meningeal, bone, or bone marrow metastases by imaging or pathology
- Severe cardiac insufficiency
- Previous allogeneic stem cell or organ transplantation
- Active bleeding or autoimmune thrombocytopenic purpura
- Contraindications to radiochemotherapy
- Positive for HIV
- Acute or chronic active hepatitis B or C infection
- History of gastrointestinal perforation or fistula, intestinal obstruction, inflammatory bowel disease, extensive bowel resection, Crohn's disease, ulcerative colitis, or chronic diarrhea within 6 months
- Unexplained intra-abdominal pneumoperitoneum
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Chongqing University Cancer Hospital
Chongqing, Chongqing Municipality, China, 400030
Actively Recruiting
Research Team
D
Dongling Zou, M.D.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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