Comparing Dexmedetomidine and Magnesium Sulphate Added to Lidocaine for Numbing in Eye Surgery Under General Anesthesia

What this Trial Is About

This research aims to compare the effects on blood circulation of two drugs, dexmedetomidine and magnesium sulphate, when added to lidocaine during a numbing injection called a preemptive peribulbar block. This is studied in patients undergoing Dacryocystorhinostomy DCR, a delicate eye surgery to open blocked tear ducts, performed under general anesthesia. The study explores how these drugs influence hemodynamic responses during surgery. Participants are randomly assigned to one of three groups. One group receives lidocaine combined with dexmedetomidine, another receives lidocaine with magnesium sulphate, and the third group receives lidocaine alone. Each treatment is administered as a 7 ml injection before surgery. The study uses a parallel design and masks both participants and researchers to the group assignments. During the surgery, researchers monitor changes in mean arterial blood pressure, heart rate, and oxygen levels for up to two hours. Patient and surgeon satisfaction with the anesthesia are assessed 24 hours after surgery. The study tracks these outcomes to understand the safety and effects of the drug combinations. The total participation time includes the surgery and follow-up assessments after 24 hours.

Hemodynamic Effect of Dexmedetomidine Versus Magnesium Sulphate as an Adjuvant to Lidocaine in Preemptive Peribulbar Block in Patients Undergoing Dacryocystorhinostomy Under General Anesthesia